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= 4^x.4^-1. - 5.2^x + 16
= 2^2x . 4^-1 - 5.2^x + 16
= 2^x ( 2^2 . 4^-1 - 5) +16
= 2^x ( 4.1/4 - 5) +16
= 2^x ( -4) + 16
= 2^x (-4) = -16
= 2^x = -16/-4
=2^x = 4
= x = 2