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p + q = -4
pq = -12
2p + 1 + 2q + 1 = 2 (p + q) + 2 = -8 + 2 = -6
(2p + 1) (2q + 1) = 4pq + 2(p + q) + 1 = -48 + -8 + 1 = -55
persamaan kuadrat baru adalah x² + 6x -55 = 0