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=> 2^-2(x + 2) = 2^3(2x - 1)/3
=> 2^(-2x - 4) = 2^(2x - 1)
=> -2x - 4 = 2x - 1
=> -4x = 3
=> x = -3/4
81^x = (3^4)^(-3/4) = 3^(-3) = 1/3^3 = 1/27