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Dada la siguiente ecuacion:
f(x) = u / v entonces
f '(x) = u'.v - u.v ' / v²
En este caso seria
f '(x) = (4x-1) - (x+2)(4) / (4x-1)²
f '(x) = -7 / (4x-1)(4x-1)
f '(x) = -7/16x²-8x+1